ORLANDO, FLA. — Hill’s Pet Nutrition brought its microbiome science to the 2025 Veterinary Meeting & Expo (VMX), the world’s largest global veterinary education conference presented by the North American Veterinary Community (NAVC). During the expo, Hill’s featured its new and enhanced Prescription Diet and Science Diet products.
“For more than a decade, Hill’s has been at the forefront of microbiome research, recognizing that a healthy gut is foundational to overall pet health,” said Karen Shenoy, US chief veterinary officer at Hill’s. “Our understanding of the microbiome’s positive impact on everything from immune function to organ health continues to grow, and we are committed to translating our scientific discoveries into nutritional innovations that support veterinarians’ daily clinical practice.”

Hill's Pet Nutrition's upgraded Science Diet formulas.
| Source: Hill's Pet NutritionHill’s microbiome expertise is built upon the collection and processing of thousands of fecal, oral, skin and urinary microbiome samples. The company directly applies learnings from data analysis to the development of nutritional interventions, including several ActivBiome+ fiber bundle and ingredient blend technologies.
These technologies include:
- ActivBiome+ Digestion, a proprietary blend of prebiotics shown to rapidly activate the gut microbiome to support digestive health and wellbeing, according to Hill’s.
- ActivBiome+ Kidney Defense, designed to activate the gut microbiome in order to reduce harmful waste products.
- ActivBiome+ Multi-Benefit, formulated to help build a foundation for lifelong health by supporting digestion, immune system and organ health with a special blend of prebiotic fibers and antioxidants.
Building on the success in products like Hill's Prescription Diet Gastrointestinal Biome, many of the new and enhanced Hill’s Prescription Diet products launching in 2025 feature this ActivBiome+ technology. Several of the products are also designed to aid veterinary professionals in managing pets with multiple conditions.
These products include:
- Prescription Diet z/d for dogs and cats, upgraded with ActivBiome+ Digestion, offering therapeutic nutrition with hydrolyzed proteins to help reduce skin irritation, scratching and digestive issues caused by adverse food reactions.
- Prescription Diet i/d for cats, upgraded with ActivBiome+ Digestion, offering nutrition formulated to activate the gut microbiome and help settle digestive upsets.
- New Prescription Diet i/d for puppies and kittens, featuring ActivBiome+ Digestion, offering highly digestible nutrition formulated to activate the gut microbiome and help settle digestive upsets.
- New Prescription Diet Multi-Organ for dogs and cats, featuring ActivBiome+ Kidney Defense, for the complexity of feeding pets that may have conflicting nutritional needs.
- New Prescription Diet Brain Care + j/d for dogs and cats, offering clinical nutrition formulated for pets with cognitive dysfunction and compromised mobility.
Hill’s also enhanced its Science Diet portfolio, bringing ActivBiome+ Multi-Benefit technology to its dry life stage products. Upgraded Hill’s Science Diet life stage dry dog and cat foods now include ActivBiome+ Multi-Benefit to support lifelong vitality with clinically proven antioxidants to support the immune system and gut-nourishing prebiotic fibers, according to Hill’s.
“Every meal is an opportunity to enhance the health and well-being of pets,” Shenoy said. “At Hill’s, veterinary professionals are at the heart of all we do, and we stand as their partners in pioneering new and improved, innovative nutrition that helps them best meet their patients’ evolving needs. Our newest advancements in microbiome science, support for pets with concurrent conditions, and life stage nutrition are extensions of our commitment to enriching pets’ health, every step of the way.”
Read more about new pet food and treat products.